In this study the potential of network-targeted transcranial direct current stimulation (net-tDCS) to modulate brain regions involved in appetite control was explored. The aim was to investigate whether stimulating the hypothalamus and its connected networks could enhance inhibitory control, with a focus on reducing overeating in individuals with obesity.<\/p>\n

Methods:<\/strong> This pilot study involved ten participants with overweight or obesity. A double-blind, sham-controlled, crossover design was used to assess the effects of anodal and cathodal network-targeted transcranial direct current stimulation (net-tDCS) on inhibitory control.
\nStimulation targeted the hypothalamus and related appetite-control networks, based on fMRI data. Participants completed a Stop-Signal Task (SST) during stimulation to evaluate response inhibition. The study compared the effects of anodal, cathodal, and sham net-tDCS, with a washout period between sessions.<\/p>\n

Findings:<\/strong> Anodal net-tDCS resulted in significantly improved inhibitory control, as shown by shorter stop signal reaction times (SSRT) compared to sham and cathodal stimulation. Participants with higher hypothalamus resting-state functional connectivity (FC) prior to stimulation exhibited better cognitive performance during anodal stimulation. All stimulation protocols were well tolerated, with minimal side effects reported.
\nThese findings suggest that net-tDCS targeting the hypothalamus network may enhance inhibitory control, with potential implications for regulating appetite and eating behaviors in people with obesity.<\/p>\n

Publication:
\n<\/strong>Ester-Nacke, T., Berti, K., Veit, R., Dannecker, C., Salvador, R., Ruffini, G., Heni, M., Birkenfeld, A. L., Plewnia, C., Preissl, H., & Kullmann, S. (2024). Network-targeted transcranial direct current stimulation of the hypothalamus appetite-control network: A feasibility study. Scientific Reports, 14<\/em>, 11341. https:\/\/doi.org\/10.1038\/s41598-024-61852-3<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

In this study the potential of network-targeted transcranial direct current stimulation (net-tDCS) to modulate brain regions involved in appetite control was explored. The aim was to investigate whether stimulating the hypothalamus and its connected networks … net-tDCS to modulate appetite control<\/span> weiterlesen →<\/span><\/a><\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[1,141],"tags":[216,217,167,187],"translation":{"provider":"WPGlobus","version":"2.10.8","language":"de","enabled_languages":["en","de"],"languages":{"en":{"title":true,"content":true,"excerpt":false},"de":{"title":false,"content":false,"excerpt":false}}},"yoast_head":"\n